4000L Stainless Steel Bioreactor

Service Hotline:0512 5888 0188

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  • Product Description
  • Product Applications
  • Product Characteristics
  • Product Information
  • Ordering Information
  • DOE.Biocell™ Pilot and Production Series Bioreactors are large stainless steel bioreactor systems designed by our company for pilot research and production. It not only combines our comprehensive understanding of reactor design parameters, flow field characteristics and cell physiology, but also includes automatic cleaning-in-place (CIP), sterilization-in-place (SIP) and other features that bring convenience to actual production. The system consists of three main parts: tank, pipe rack and control cabinet. The control system adopts Siemens S7-1500 PLC controller + touch screen + host computer mode, all parameters of the control system can meet the needs of cell batch culture, flow plus culture and continuous culture.


  • Widely used with suspension culture and microcarrier culture of animal cells:

    CHO cell culture

    SF9 insect stem cell culture

    Vero cell culture

    BHK21 cell culture, etc.

  • (Advantages of industrialized production)

    GMP Hygienic Design    Convenient one-button operation

    data visualization       Operate without worry

  • model number

    BS 50L

    BS

    100L

    BS

    200L

    BS

    500L

    BS

    1000L

    BS

    2000L

    BS

    3000L

    Overall module size

    Module size

    1450*2300*3000

    mm

    1650*2350*3000 mm

    1650*2350*3050 mm

    1900*2500*3300 mm

    2000*2600*3600 mmplatformless

    2500*3600*4100 mmIncludes platforms

    2850*3620*4750

    MmIncludes platforms

    3000*3800*5100

    MmIncludes platforms

    Stainless steel tanks

    working volume

    50L

    100L

    200L

    500L

    1000L

    2000L

    3000L

    Inner tank height

     783mm

     912mm

     1131mm

    1485 mm

     1709mm

    1980mm

    2320mm

    Inner tank diameter

     350mm

     450mm

     550mm

     800mm

     950mm

    1300mm

    1500mm

    Inner tank volume

    73L

    140L

    260L

    770L

    1268L

    2758L

    4290L

    Inner tank material

    316L stainless steel

    Jacket material

    304 stainless steel

    Jacket volume

    8L

    18L

    25L

    40L

    80L

    130L

    150L

    manufacturing standard

    ASME BPE-2019, PED welding standards, 2 Pressure vessel quality GB/T150.1~150.4-2011, ISO9001:2000

    polishability

    interior:0.2~0.4 μm;in addition:0.8 μm

    Polishing accuracy of the surface in contact with the material Ra≤0.4

    Working medium

    Inner tank: raw material/saturated steam; jacket: chilled water/saturated steam

    Configuration Interface (Optional)

    Material and gas inlet and outlet: inoculation valve port, refill valve port, in-line sampling port, bottom valve, surface vent, deep vent, safety rupture disc;

    Operating status visualization window and searchlight,

    Monitoring probe interface: pH/DO/level/pressure/foam, etc.

    control unit

    PLC

    Siemens (company name)

    user interface

    Industrial-grade color touch screen

    temperature control

    Heating form

    temperature control jacket

    Temperature control method

    PID, temperature regulation with plate heat exchanger, electric heating jacket and cooling water

    Temperature control accuracy

    Display accuracy: 0.1°C, control accuracy: ±0.1°C

    Temperature control range

    Ambient temperature above 5°C ~ 60°C

    Mixing systems

    stirring power

    Magnetic force, servo motor, PID control

    control accuracy

    digital display,±1rpm

    Mixing speed

    20~300 rpm

    slurry

    Inclined-blade/spiral/propeller/turbine/propulsion, etc.

    Monitoring Probes

    pH

    Mettler/Hamilton, 0-12, PID control, accuracy: ±0.02

    pH control method

    PID, done under the control of an acid/base peristaltic pump or CO₂ mass flow meter

    DO

    METTLER/HAMILTON, 0-200%, PID control, accuracy: ± 1%

    temp

    Pt100, PID control, digital display, ±0.1°C

    air supply system

    flow rate regulation

    Air/CO₂/O /N: rotameter, solenoid valve or mass flow meter

    control range

    Rotor flow meter: according to process requirements

    Mass flow meter: according to process requirements

    gas distributor

    Ring form/single tube/micropore diffuser

    Intake filters

    0.2μm, PTFE

    exhaust gas control

    Automatic tank pressure control range 0~0.2 MPa, control accuracy ±0.005 MPa

     

    Exhaust filter

    0.2μm, PTFE; filter housing with heating blanket

    Exhaust condenser

    316L Stainless Steel

    Charging system (customizable)

    peristaltic pump

    PID interlock control

    Operation and Function Expansion

    Sterilization method

    Automatic in-line autoclave sterilization

    Cleaning method

    Automatic (CIP cleaning station required) / manually controlled cleaning

    training program

    Siemens PLC system, cell culture specific program

    Amplification Unit

    Weighing module;

    Automatic lifting device for tank lids;

    Operation status visualization window and searchlight;

    Online detection of ORP, foam, liquid level, light, etc.

    public works

    chilled water

    Pressure: 0.2 MPa; Temperature: not more than 10 °C

    purified water

    Pressure: 0.2 MPa

    Water for Injection

    Pressure0.2 MPa

    compressed air

    Pressure0.6 MPa

    industrial steam

    Pressure0.3 MPa

    pure steam

    Pressure0.2 MPa

    operating environment

    Relative humidity ≤80%, non-condensing

  • ordering number:0512-588801888

    Inquiry Email:womeishengwu@szwmbio.com

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Contact details

  • Website:
  • http://en.suzhouwomei.com/
  • Email:
  • womeishengwu@szwmbio.com
  • Address:
  • No.23, South side of Fenghuang Avenue, Fenghuang Town, Zhangjiagang City, Suzhou, China

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